I’m using it now. I don’t know if Windows 10 USB 3.0 drivers are better (well, they didn’t come with WIndows 7) or it was simply the clean install of Windows 10…
A lot of the USB comes from the data signals being next to the power and ground signals, they add a lot of hash. The Corning 3.Optical also uses fairly thin power and ground wires which lowers the relative contribution from them compared to a local power supply with more “oomph.”
I also use a local powered USB hub after the Corning cable next to the DS. With nothing else on this hub the power is pretty quiet and if you want to go nuts you can get a linear power supply for that last hub. (I have a spare dedicated outlet which is certainly overkill, but what the heck. 
)