Next minimal upgrade steppe for SQ

Here is my set Up what would be the minimal next step up for Sound Quality.

WD usb2 2TB external HD Only Music aiff’s on it + Time Machine BackUp

MacBook Pro 2013 8GB RAM 256 internal Flash drive usb3

AudirvanaPlus Always very latest Version

Regen

ifi DAC nano latest driver iFiHDUSBAudio_dfuapp5.1A.sh

Oyaide neo d+ Class A USB 2.0 to MacBook

MusicLink Transparent Interface cables

Parasound 2100 Classic Preamp

Reference B&K 200.2 S2 Power amp 225W RMS

Paradigm 100 S series speakers

Klipsch Reference R-10SW Sub

Thanks

What is your budget?

If the above is your whole system, no other sources, I would replace the preamp and dac with a Directstream Jr. It would replace both of those components.

Or if you are mostly happy with the sound, start working on cleaning up your power, a regenerater or power conditioner, it all depends on budget.