I haven’t attempted to try to do any sort of sonic comparison, if that’s what you’re asking. The guy who put together my custom Mini server (same as Paul’s) felt it was worth using a TB drive - it may be “quieter” if it requires less work from the computer - not sure. I would think USB3 would be fast enough for almost anything you could typically throw at it audio-wise, since it’s fast enough to record and play back multiple channels of high-res audio simultaneously.
I have come to realize that, despite its ubiquity as a digital audio protocol of choice, USB isn’t the best - mostly due to all the things that can affect it negatively, sonically. But if it’s just going from a drive to the computer as data (that is, not being output by a player as music) I’m not sure it would matter.