The question you’re dealing with is kind of step 1 for Mac-based audio. If Audio MIDI Setup is even part of your thinking then you’re letting the CoreAudio system in macOS do things to your audio instead of passing the data directly out to your DAC.
“Do things” means sample rate conversion and mixing. For your 99% listening as described, my advice would be to set Audio MIDI to 44.1/24 so that the Mac is not doing upsampling. The DS DAC’s built in upsampling is way better.
Longer term you should look at a different workflow. For instance, if you use Roon or Audirvana they will grab “exclusive mode” use of the DAC and simply send the audio data directly to it rather than having macOS “do things”. Both Roon and Audirvana support Tidal streaming.