Does anyone use Isolation transformers any more? Oneac, Powervar or do I get rid of these?

20 yrs ago, Isolation transformers were touted as noise reduction units . Now I have a larger PS Audio regenerator powering several components.
Ive got a few Oneac and a larger Powervar transformers.
Is there anywhere in home these are useful or do I get rid of these?
I am using a Triplite Isobar surge protector in front of my Notebook power suppy. Is there any benefit there (a headphone amp is on that same surge protector)