My amp is a fully differential amp, so I use the bottom connection in the diagram. I cannot give advice on connecting to a BHK250, but the method of connection is based on the amplifier used.
When using the high level connections to drive your REL Sub, some have found that also connecting the RCA level to your preamp ends noise. You aren’t actually using the RCA connection for sound, you are just using it for the ground connection between the preamp and the sub.
I used to use the High Level for normal listening, and the RCA for multichannel. But now that I have separate Music and theater setups I don’t do that anymore. Anyway, don’t be afraid to connect the RCA between the sub and the Preamp. Even when using the preferred High Level.
On my setup, two subs, I use both the red and yellow cables twisted together at both ends. I do not use the black wire on amplifier end. Someone will shout that this absolutely cannot work. They will be absolutely wrong. It works great.
If you don’t have a REL sub, ignore all of the above.